College of Science News

02:47 PM
September 22

SUSTech Chuang-Chuang Li’s group publishes top-tier research paper on Type II cycloaddition reaction

Recently, Professor Chuang-Chuang Li’s group from the Department of Chemistry at the Southern University of Science and Technology (SUSTech) first reported a type II intramolecular (3+2) dipolar cycloaddition reaction for the syntheses of various bridged bicyclo[m.n.2] ring systems. This method was used as a key step accomplishment of asymmetric total synthesis of natural product nakafuran-8. The computational study was carried out to explore the regioselectivity, chemoselectivity, and diastereoselectivity of type II (3+2) cycloaddition.

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